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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3196d5a87d8b62abf0efe8b17883bdf1bb0cb2190002f45cbd337deda61789a5' 
  AND token = 'WDdj1CtC1XnNFWGs6+DWdpN9FkMv0PeTG8U9MwIlTAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}