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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fb401d786010f1219a38f9944ecbfabcf8256e73d9589592376924f2cd9282e' 
  AND token = 'H+PlT8XAbWeTmq+b9eHDtlGGlIIAfZSBdPkQe6H3Rjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}