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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '738b5f5e93bf9f2f54ee827d8aeafac162e1c78427e757f8fa3d562cab9cc363' 
  AND token = '69zHQMCERCJEeqlXti+dojW9xa934UToVhS8TrIgMrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}