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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd04785b1023a08a286a3be61054039576e0b6a7e7a2ebc17ac4d54c2b7a60f43' 
  AND token = 'OUirf4rgAiRS7YZ7bhhyTci3sVdJgUyqtFQlBIiDdXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}