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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cba4d6a711426d692d705eefe9e46ac2112a29db08b896c053368a062b8e0ee' 
  AND token = 'N3nEn6G6RKXTF4f0Y/eRp31WhQSd+Ye7YCfIoJJXV+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}