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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8294e2c00487650ebdf0c511f24115dba4657ba450ef44a345802afc0e1c0ef' 
  AND token = '/qocUTO97vHWZAA7Pmer+suC5GEaIl29BVMEc2XSHgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}