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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15cb9864223fee003c2b0399150f83dcaf979e1885f2e9da05c9a424a1efba4b' 
  AND token = 'do50Riz8bkD9dT0oCMSp/h/fv/RI9A3cs5B24/d99VA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}