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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ff52802e36353b1d1b0a7bea1c5ec58a263bf1c1d5d270e9e55bf5f47e07c19' 
  AND token = 'MMow80/LEZAR8tVXFbY8QybuIiaBC0T7rfvYcmdt+e0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}