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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a3cd249dd1c5a4a38c4525e7794d34dec3d1e15c32aca6f678c7a701ac2b170' 
  AND token = 'Nyp91GYC0WGDvbqfjEBAVcUJNwj32b2rSe2M6kmI8rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}