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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0bbd9004fd90cc24102e975c25ea4d4066ea30aa3f963853d4ffd214c2c4f3e' 
  AND token = 'QAyXa6EmmTVKETdKJgFsm9ClVUf9uqNoQMFa+IrPbdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}