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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe6240f4a5ae17c970d7ec8f272e620737fa97ff321b89af11c27efbb3a62a99' 
  AND token = 'RfSTOaKbpguBQygPdpKE4bM09vePC5YVaiui8DeXC60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}