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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '895d14a1177372f657fb6ff42b4b5e6841eee73142b9eb41609163271b73bd34' 
  AND token = 'uHjg41r+e3l7koxS3LFx2P5ctRyM9IHHjAn0dOoFTWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}