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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b43a86af1990c92d1401b7298562f819bc178b9a06f99138b3dcd0e1095009ba' 
  AND token = 'Y7tv+pY0wQH903azuKcCO2Z8nA/L/OGwecJqZCbOg04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}