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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b972814502f23e24a11a72fd8a6dde0d225b4505483e72e27b0fc84c99041d4e' 
  AND token = 'cMfGjt8fmQZev6b+GeVap1BXAI/G783/P3pqxZXfJsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}