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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66749e2b6a6116a8a70644a1212fac7d9c08896b6a0179ed8ac4fb978694025' 
  AND token = 'Dii0II+2Y8D0uEE8cKhzEyU8/0Cldkk7nGfX3hZ25V4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}