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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd035d2a1727df85d1bfb0115d1027ac6d0bd32ce82d51281726094407f453680' 
  AND token = '901Kz1bzqstyCLKCNAUlxmG2/0FxNworf6KDW7CFF00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}