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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb9e25db6010c8dfa1455edbb81c7061d6c67473a99390d8c72ad2d876e58f07' 
  AND token = 'YpH3uzUj8yDcq1vOOe6DwO/t8e4rV8MxdKo7MAfV9/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}