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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a5d0bcae9fde69e3234569a54a8d6aad12a3d952f6dcfc31ce1377ae08a1f4' 
  AND token = '68Uea0Az1pxbWQpq7iry49vBuylapBbHxEdesCAo8Tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}