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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe4c3772e9808201276c504557cbac1613798f9008f0d78dcdfba23146a18a47' 
  AND token = 'puT2y/luvhkiyCLTJneoyU7ZY0TNiH3h8KPiM4H/G0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}