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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b1326e5712904aac625084afe2efce404beb93462a5f947c5f15ce290fe4d1' 
  AND token = 'DgJ3NBvYxx4y7x6b/WF6PpvT5GI8OLNlA4D+wY/ir7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}