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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3f56143194ac5bf161cc500cb01ddb0c642d012f87a6e469724b1753f9d832' 
  AND token = 'e5q2Bbv6pF+G/Mr189TnH+JORxLI9169pZEOzBzZd80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}