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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d513b8449afd1dcb344a4f12baf8fbe1f05b80157e929d661c9e47bebdddc3c' 
  AND token = 'vtJPlZHU4LMhKnoxkcKrVTn3aYyFdN67dKnGHu/cSF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}