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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7623adf4f675cd6fc5e163b8a43365714d04eda85c91c648a6948b12dd91a4c2' 
  AND token = 'yNi+WGBIXY2SbXnmG0cYmAotl8tLXocveYfvRrIuSB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}