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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '810e882e078c8a3ed2a5d159890f11452a6313c6aa7fbf61bdf9f2a0779b5e86' 
  AND token = '6BRC92qSo/bCCWEjeEJcxnFpLxSHBhcb2mYHTVa/Ho8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}