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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b72eb704b17a83e203ef1d428376707d458addc7937bcb0b19d177a7265c681' 
  AND token = '394+FeUVb21+ypKjN+76PzjEa1V3fgm6OhjbX1wyDRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}