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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e04fcd77713e530fe4ccd1f006d74864777150bba700a670f537c5f2461edc1' 
  AND token = 'KX/frHKw/pmBzVhzyGdcLZyeMIEW0fU1RItjjihM3n0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}