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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9d5b523b0c279671b19d278492794a6b8907f8361f3e66c608ed9369dc728c9' 
  AND token = 'lbQYw/F4ZrKpuGLgnMCIgrFa2CqALi70ou71CQBWycI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}