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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1800c60ae1e0750499fe9dcc8c6593aa4cb8f41ebc75e0824b9aa35fa1593b1' 
  AND token = 'FHHlrx0p89zp7LQopvFVMYr5gcYO7c34FL5nzGNNfNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}