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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e80df0bd0e0b7d5fa8696a2ab353afe65fba0dce280d68d52f7282b7ab5c352' 
  AND token = '+c7sZZUR6/Wl5AVVpHL+BW+lw0qq05kgxQkw9BdX0fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}