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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c911583bb7b019590c29bfee62445c10394489a355474314faa85d09f1d17c' 
  AND token = '+z0L5zLRlxOBq3qQn0hRTNKoI77++G7IOVnP4aopAXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}