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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58569c0a3759bec09e8e256b6bdb8e1e9213e8e66f6f1ad017a84fde50ae6b18' 
  AND token = '1cN3W2bcz+OpCbvhdWiO/QZAEgJ7pixaYiGi8Ut3nDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}