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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f0c97ba7871def906f2c331b256a7ae126cbc4adc8cb0a138bf6ebcd4201ca' 
  AND token = 'IxQTzSpTLW8S6BzGEeNG+GwckSoen2HsE10swVJtVUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}