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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4253e66538a8c37f15927bc3362df8569534b43a3dde29aed10b342b3bc6a1bf' 
  AND token = 'G4wBomKyvmoW77Sb0ddJ/TbGmq9lo+1Pvc/3jZdZeJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}