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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9720b173986f68a56dc8f546c1ce053b7e75612564943f187a2b3b6be332c2e6' 
  AND token = '45Uz6XZRzkX/B3ExQRZd4eTn9/+T1gRMiOgi08PJVEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}