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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd66b60d026fa3d8c7939ec813472492a601998e9049009d4525b873a2886ea8f' 
  AND token = 'KsLuQrlC73r/98fp3FpYE5Kf2edJAgWLspV4NmnAjBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}