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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99638e53493cbc847b889d9be4042d4f626e609108c34d8b8b53ba6236d2b247' 
  AND token = 'I/W8+IifgfHlHGo8v9ChMXi66GuYSrR+wcamTBmn39U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}