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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c5876a7c664ffd1044a4b3e34618b9f0b412fd379e75d90176ecd2cc68477b6' 
  AND token = 's5lsHZrS3zzvESgl3b0RtEAtKgKbqCaBxc32smgiPMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}