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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6640ae1420fa9624a7f03a674b4e5a32d6c0858c964fab732b1b54ed5de8124' 
  AND token = 'JzVOiqOshe67dkjzIUN3w1k2sT0dwZtjQsbmYu2H+iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}