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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd313c4044c2dcdb682c035ab8248d6a89474e4f50e856e1547df2d885a6dc6a' 
  AND token = 'wpuaMuz6TAJ/BG2eSIaZHiBPJPNQEdAdC71yObBv3Hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}