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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bfafa81e9e09084b9d28110c52d38f1faa6d3411a91bb0fa29cfc72568d11ab' 
  AND token = '21mOut9ayPTON10hRVz+f3vsb5tA/pedtgG5vEhwnrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}