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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e54300a60e91d6a3eaff49be5ad78e0a2e589a8c36e94cf5ba7431c04155f1d' 
  AND token = 'yQ4XQV2HNL9jUoYtWJB5oq+/6n2MTQp93TQQMIE2lAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}