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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e4e8b5a8dacb1ff7bfb6ae14e68b1e3520ff50dd968c009282cbea81ebd1835' 
  AND token = 'zOJ0DO7E/Yih9ieeuGc1mmJAaauwWbwM/IoBmvUJiL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}