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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae43fcc3ecf41591d02e1df3f7cbf0fcc11e506049cac27852ad04672dc2671f' 
  AND token = '6RT8VgU29VdA8UBIgTwUQgKeX2oDBhjPBl/n0JWGHyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}