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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b110f60a6ef8ff19abff9b8d827266427a276d54201c7a207a5df216a3be3068' 
  AND token = 'vJ9ilt5Vb/k7l/zLB44Opvv1ZcYSLFTYO2Bd6WL4PQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}