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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c5135372dd68465c42e7cc7e103f7fe44abd2273f60429957f62fc575362e29' 
  AND token = '9eZuJiXrUwB3MveSuvUsYq1u2ZW5GE8/hdr1uTwkpAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}