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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9f1da245f1ecb868434b35ca4d585916f2868f8d66707b34cd6e2420eafa39b' 
  AND token = 'n4DATNNUh16W1238lpUxgx2xXMVItxdgvzNi/rYYqmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}