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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e33391b9c0ae908e7cb806545b73df2c490a5ff7c07469bfb01f5230939f07b5' 
  AND token = 'SgISfQDJojxxeauSjr8dgZIenbaYGTjdie97oox0oP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}