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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f13eaed4e5427fdc45b5debd3d3691511e2970a6b12ac23c303890c33de3cade' 
  AND token = 'ELInv7JCPNJ1GHpCyWrKaY+CwgsC8WJK0RVLV5NQQ9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}