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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa0af350291d4aba75f21928d7be8330477a03a40eaeb42001a9df7054c0f5c9' 
  AND token = 'Grn1H00PznTw2w+DJ7/OwO9hK0UUs791q5RJ0ZY1iXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}