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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a89d20dca064bb3a5607eb474a9ea0d02af9c12bcb4a9c26d5df06a017e97dcf' 
  AND token = 'jG3CN8927H/QDP5fWFvO5yHZwbLIiHsQ4edVJaFnCDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}